Pyridoxal 5′-Phosphate Monohydrate | 41468-25-1
Product Description
Pyridoxal 5'-phosphate monohydrate (PLP monohydrate) is the active form of vitamin B6, also known as pyridoxal phosphate.
Chemical Structure: Pyridoxal 5'-phosphate is a derivative of pyridoxine (vitamin B6), consisting of a pyridine ring linked to a five-carbon sugar ribose, with a phosphate group attached to the 5' carbon of the ribose. The monohydrate form indicates the presence of one water molecule per PLP molecule.
Biological Role: PLP is the active coenzyme form of vitamin B6 and serves as a cofactor for a wide variety of enzymatic reactions inthe body. It plays crucial roles in amino acid metabolism, neurotransmitter synthesis, and the synthesis of heme, niacin, and nucleic acids.
Enzymatic Reactions: PLP acts as a coenzyme in numerous enzymatic reactions, including:
Transamination reactions, which transfer amino groups between amino acids.
Decarboxylation reactions, which remove carbon dioxide from amino acids.
Racemization and elimination reactions involved in amino acid metabolism.
Physiological Functions
Amino Acid Metabolism: PLP is involved in the metabolism of amino acids such as tryptophan, cysteine, and serine.
Neurotransmitter Synthesis: PLP participates in the synthesis of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA).
Heme Biosynthesis: PLP is required for the synthesis of heme, an essential component of hemoglobin and cytochromes.
Nutritional Importance: Vitamin B6 is an essential nutrient that must be obtained from the diet. PLP is found in various foods, including meats, fish, poultry, whole grains, nuts, and legumes.
Clinical Relevance: Vitamin B6 deficiency can lead to neurological symptoms, dermatitis, anemia, and impaired immune function. Conversely, excessive intake of vitamin B6 can cause neurological toxicity.
Package
25KG/BAG or as you request.
Storage
Store at a ventilated, dry place.
Executive Standard
International Standard.
