Iopamidol|60166-93-0

Iopamidol, also known as iodopeptidol, iodopentanol, iopamidol, iopamidol, iodobidol, iopamisone, is a non-ionic water-soluble contrast agent, which is a drug for imaging diagnosis. Its chemical structure is The amide compounds of triiodoisophthalic acid derivatives have low toxicity to blood vessel walls and nerves, good local and systemic tolerance, low osmotic pressure, low viscosity, good contrast, stable injection, and very little deiodination in vivo. Myelography and in patients with high risk factors for contrast reaction. After intravascular injection of iopamidol, it is mainly excreted through the kidneys. T1/2 varies with renal function, generally 2 to 4 hours, and is mainly excreted in the original form with urine, 90% to 95% is excreted in 7 to 8 hours, and almost 100% is excreted in 20 hours. In vivo, iopamidol is not metabolized, does not bind to plasma proteins, and does not interfere with isoenzymes. Due to the high content of iodine, this product attenuates X-rays to achieve the purpose of contrast imaging, and is suitable for X-ray contrast for intravascular injection. Iopamidol is clinically used for various angiography, such as cerebral arteriography. Cardiovascular angiography includes coronary arteries, thoracic and abdominal arteries, peripheral arteries, veins, and digital subtraction angiography. And urinary tract, joints, fistula, spinal cord, cistern and ventricle, selective visceral arteriography. Enhanced scan in CT examination.